Lamotrigine Eye Side Effects: Quick Guide for Patients

If you’re taking lamotrigine for seizures or mood disorders, you might wonder if the drug can mess with your eyes. The short answer: it can, but serious problems are rare. Most users notice only mild, temporary changes that go away on their own.

Typical eye complaints

People on lamotrigine sometimes report blurred vision, double vision, or a slight glare around lights. These sensations usually appear within the first few weeks of treatment and often improve as your body adjusts. A small percentage also notice dry eyes or a mild itching sensation. If you experience any of these, try lubricating eye drops first – they’re cheap and often effective.

When to get serious

Although uncommon, lamotrigine can trigger more concerning issues like sudden loss of vision, severe eye pain, or swelling around the eyes. These symptoms could signal an allergic reaction or an impact on the retina. If any of these pop up, stop the medication and call your doctor right away. Rapid action can prevent lasting damage.

Another red flag is a rash that spreads to the eyes. Lamotrigine is known for skin reactions, and when a rash reaches the eyelids, it can cause swelling and blurry sight. Treat it like any severe rash: seek medical help immediately.

Older adults and people with pre‑existing eye conditions (glaucoma, cataracts, or dry‑eye syndrome) may be more sensitive. Make sure your eye doctor knows you’re on lamotrigine, especially before any eye surgery or new eye drops.

Don’t forget to schedule regular eye checks. Even if you feel fine, a yearly exam can catch subtle changes early. Your optometrist can compare your vision baseline before you start the drug and spot any drift over time.

If you’re worried about side effects, talk to your prescriber about dose adjustments. Often, slower dose increases reduce the chance of eye irritation. Some clinicians also switch to a different anticonvulsant if eye issues become persistent.

Bottom line: lamotrigine can affect your eyes, but most problems are mild and reversible. Keep an eye (pun intended) on any visual changes, stay in touch with your healthcare team, and don’t ignore sudden, severe symptoms. Your vision is worth the extra attention.