Fludrocortisone – What It Is and When Doctors Prescribe It

Fludrocortisone is a synthetic mineralocorticoid that mimics the hormone aldosterone. It helps your body keep sodium and water, while getting rid of excess potassium. Because of this, doctors usually give it to people whose adrenal glands can’t make enough natural hormones.

The most common reasons for a prescription are Addison’s disease, other forms of primary adrenal insufficiency, or a salt‑wasting disorder that drops blood pressure too low. Some patients who have had certain kidney surgeries also benefit from the extra mineralocorticoid effect.

When you start fludrocortisone, your doctor will check blood pressure, electrolytes (especially sodium and potassium) and overall fluid balance. The goal is to keep you stable without causing swelling or high blood pressure.

How to Take Fludrocortisone Safely

The usual adult dose ranges from 0.05 mg to 0.2 mg once a day, but your exact amount depends on lab results and how you feel. Most people take it in the morning with food so it’s easier on the stomach and fits into daily routines.

If you miss a dose, take it as soon as you remember—unless it’s almost time for the next one. In that case, skip the missed tablet and continue with your regular schedule; don’t double up.

Fludrocortisone can interact with medicines that also affect sodium or potassium levels. Common culprits are NSAIDs (like ibuprofen), certain diuretics, and ACE inhibitors. Tell your pharmacist about every drug you use, including over‑the‑counter supplements.

Typical side effects include mild swelling in the ankles, a rise in blood pressure, headache, and sometimes low potassium levels that can cause muscle cramps. If you notice sudden weight gain, severe swelling, or an irregular heartbeat, call your doctor right away.

Common Questions About Fludrocortisone

Can I drink alcohol while on fludrocortisone? A small amount won’t usually cause problems, but heavy drinking can raise blood pressure and worsen dehydration. Keep it moderate.

Is the medication safe during pregnancy? There’s limited data, so doctors weigh benefits against potential risks. If you’re pregnant or planning a pregnancy, discuss alternatives with your healthcare provider.

How should I store fludrocortisone? Keep it at room temperature, away from moisture and direct sunlight. A bathroom cabinet is fine as long as the bottle stays closed.

What if I travel abroad? Pack enough tablets for your whole trip plus a few extra days in case of delays. Carry them in their original labeled container and keep a copy of the prescription handy for customs.

Lastly, always bring your latest lab results to follow‑up appointments. Blood tests show whether your sodium, potassium, and blood pressure are staying in the right range. Adjusting the dose is usually a matter of fine‑tuning based on those numbers.

Fludrocortisone can feel like a lifeline for people with adrenal problems, but it works best when you stay aware of dosage, side effects, and interactions. By following these practical tips, you’ll keep the medication doing its job without unwanted surprises.